Research and Development
Research and Development Process
The amount spent on research and development is rising while the number of innovative new drugs approved is falling. This is in spite of the new technologies now being used in R&D. How can the R&D process be improved to increase the success rate and lower costs? Are there specific challenges for diseases that principally affect developing countries?
Documents
- R & D System is Failing to Meet Health Needs in Developing Countries (Eng/Spa) (November 2004)
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A Needs-Based Pharmaceutical R & D Agenda for neglected diseases (July 2004) Els. Torreele, Martine Usdin and Pierre Chirac (MSF/ DNDI)
pdf, 751kb - Surmounting Challenges: Procurement of Antiretroviral Medicines in Low- and Middle-Income Countries: The Experience of MSF (November 2003)
- MSF briefing on fixed-dose combinations (FDCs) of antiretroviral drugs - two pills a day saving lives (February 2005)
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Assessing claims about the cost of new drug development: A critique of the public citizen and TB Alliance reports | Tufts University | 2004
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The Pharmaceutical Innovation Platform- Sustaining Better Health for Patients Worldwide | IFPA | 2004
pdf, 494kb -
Innovation and Stagnation: Challenge and Opportunity on the Critical Path to New Medical Technologies | FDA | 2004 [pdf 245kb]
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Genomics and world health: report of the Advisory Committee on Health Research | 2004 [pdf 36kb]
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Scientific Blueprint 2004: Accelerating global efforts in AIDS vaccine research and development [pdf 300kb]
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Contraceptive Research, Development, and Use: Lessons from Norplant | Institute of Medicine | 1998
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Genomics and Health- Key Documents (SciDev.Net web site)
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Working paper on priority infectious diseases requiring additional R&D [pdf 196kb]
- Rebuilding Big Pharma's Business Model
Feature articles
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Genomes for medicine (Nature web site) | 27 May 2004
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Drug Discovery | Science, Vol 303, Issue 5665, 1729 | 19 March 2004 (Special online collection of articles)
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Playing Hide And Seek The Deadly Way- HIV continues to elude researchers (Nature web site) | 2 February 2004