Guidelines for the treatment of malaria. Second edition
The World Health Organization's Guidelines for the treatment of malaria. Second edition provides evidence-based and up-to-date recommendations for countries on malaria diagnosis and treatment which help countries formulate their policies and strategies.
In scope, the Guidelines cover the diagnosis and treatment of uncomplicated and severe malaria caused by all types of malaria, including in special groups (such as young children, pregnant women and HIV/AIDS patients), in travellers (from non-malaria endemic regions) and in epidemics and complex emergency situations.
The first edition of the Guidelines for the treatment of malaria was published in 2006. The second edition introduces a new fifth ACT to the four already recommended for the treatment of uncomplicated malaria. Furthermore, the Guidelines recommend a parasitological confirmation of diagnosis in all patients suspected of having malaria before treatment.
The move towards universal diagnostic testing of malaria is a critical step forward in the fight against malaria as it will allow for the targeted use of ACTs for those who actually have malaria. This will help to reduce the emergence and spread of drug resistance. It will also help identify patients who do not have malaria, so that alternative diagnoses can be made and appropriate treatment provided. The new Guidelines will therefore help improve the management of not only malaria, but other childhood febrile illnesses.
The Guidelines for the Treatment of Malaria. Second Edition can be purchased through the WHO bookstore at: www.who.int/bookorders. Customers in developing countries will take advantage of a discounted price. Those who cannot purchase online can contact our sales agents (list available in the bookstore homepage http://www.who.int/library/services/en/) or our sales office in Geneva at email: email@example.com or fax +41 22 791 4857.
Related policy recommendations
- WHO policy brief for the implementation of intermittent preventive treatment of malaria in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP) (April 2013)
- WHO policy recommendation on seasonal malaria chemoprevention (SMC) for Plasmodium falciparum malaria control in highly seasonal transmission areas of the Sahel sub-region in Africa (March 2012)
- WHO policy recommendation on Intermittent Preventive Treatment during infancy with sulphadoxine-pyrimethamine (SP-IPTi) for Plasmodium falciparum malaria control in Africa (March 2010)
Other key documents
- Information note on delayed haemolytic anaemia following treatment with artesunate (2013)
- Management of severe malaria – A practical handbook. Third edition (April 2013)
- Updated policy recommendation on single dose primaquine as a gametocytocide in Plasmodium falciparum malaria (October 2012)
- WHO Position statement on the effectiveness of non-pharmaceutical forms of Artemisia annua L. against malaria (June 2012)
- T3: Test. Treat. Track. Scaling up diagnostic testing, treatment and surveillance for malaria (April 2012)
- Intermittent preventive treatment for infants using sulfadoxine-pyrimethamine (SP-IPTi) for malaria control in Africa: implementation field guide (September 2011)
- Universal access to malaria diagnostic testing – An operational manual (September 2011)