Malaria

Methods manual for product testing of malaria rapid diagnostic tests

January 2012

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Authors:
WHO, FIND, CDC

Publication details

Number of pages: 189
Publication date: 2012
Languages: English

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Overview

This procedure manual details a protocol for the product testing of antigen-detecting malaria rapid diagnostic tests (RDTs) using samples of frozen parasites prepared for this purpose.

The manual describes a protocol to:

  • assess sensitivity and specificity of RDTs against a specimen bank consisting of recombinant antigen, culture-derived parasites and wild-type parasites, and parasite-negative blood samples;
  • assess the stability of RDTs at various temperatures;
  • describe aspects of RDTs affecting ease of use in the field; and
  • record results in a database.