Guidelines on HIV and infant feeding 2010
Principles and recommendations for infant feeding in the context of HIV and a summary of evidence
Overview
Significant programmatic experience and research evidence regarding HIV and infant feeding have accumulated since WHO's recommendations on infant feeding in the context of HIV were last revised in 2006. In particular, evidence has been reported that antiretroviral (ARV) interventions to either the HIV-infected mother or HIV-exposed infant can significantly reduce the risk of postnatal transmission of HIV through breastfeeding. This evidence has major implications for how women living with HIV might feed their infants, and how health workers should counsel these mothers. Together, breastfeeding and ARV intervention have the potential to significantly improve infants' chances of surviving while remaining HIV uninfected.
While the 2010 recommendations are generally consistent with the previous guidance, they recognize the important impact of ARVs during the breastfeeding period, and recommend that national authorities in each country decide which infant feeding practice, i.e. breastfeeding with an ARV intervention to reduce transmission or avoidance of all breastfeeding, should be promoted and supported by their Maternal and Child Health services. This differs from the previous recommendations in which health workers were expected to individually counsel all HIV-infected mothers about the various infant feeding options, and it was then for mothers to decide between them.
Where national authorities promote breastfeeding and ARVs, mothers known to be HIV-infected are now recommended to breastfeed their infants until at least 12 months of age. The recommendation that replacement feeding should not be used unless it is acceptable, feasible, affordable, sustainable and safe (AFASS) remains, but the acronym is replaced by more common, everyday language and terms. Recognizing that ARVs will not be rolled out everywhere immediately, guidance is given on what to do in their absence.
Related links
Related documents
- HIV and infant feeding 2010: an updated framework for priority action
-
Antiretroviral therapy for HIV infection in adults and adolescents
Recommendations for a public health approach (2010 revision) -
Antiretroviral drugs for treating pregnant women and preventing HIV infection in infants: towards universal access
Recommendations for a public health approach (2010 revision) -
Antiretroviral therapy for HIV infection in infants and children
Recommendations for a public health approach (2010 revision)
Annexes
-
Annex 1 - Scoping questions for systematic reviews and issues to be addressed in revision of recommendations
pdf, 37kb -
Annex 2 - Protocol and summary of systematic review of HIV-free survival by infant feeding practices from birth to 18 months
pdf, 227kb -
Annex 3 - Search strategy for other scoping questions
pdf, 41kb
Annex 4 - GRADE profiles
-
4a - Grade profiles 1-3. HIV-free survival by infant feeding practices 0-18m
pdf, 108kb -
4b - Grade profile 4. Nutritional adequacy of replacement feeds (excl. FF)
pdf, 55kb -
4c - Grade profile 5. Replacement feeds and survival vs. AFASS conditions
pdf, 84kb -
4d - Grade profile 6. Heat-treated breast milk
pdf, 66kb -
4e - Grade profile 7. Feeding HIV-infected infants
pdf, 73kb -
4f - Grade profile 8. Breastfeeding and maternal health
pdf, 67kb
-
Annex 5 - Individual evidence summaries of all studies included in the systematic review of HIV-free survival by infant feeding practices from birth to 18 – 24 months
pdf, 803kb -
Annex 6 - Consolidated risk-benefit tables
pdf, 246kb
Annex 7: Model to assess the impact of different infant feeding practices and antiretroviral interventions on infant HIV free survival