Dengue, dengue haemorrhagic fever and dengue shock syndrome in the context of the Integrated Management of Childhood Illness
Dengue is not included in the generic Integrated Management of Childhood Illness (IMCI) algorithm but it is an important differential diagnosis of fever in children presenting to first-level health facilities in tropical Asia and Latin America. There has been no previous summary of existing dengue guidelines to explore their usefulness in the context of IMCI and to identify questions for research.
This review summarises the virology, transmission and pathogenesis of dengue, its significance by region, and its epidemiologic, demographic, and clinical features; assesses existing diagnostic guidelines; evaluates the evidence base for current treatment guidelines; examines IMCI adaptations of dengue algorithms; and discusses experience with home management of dengue and recognition of specific clinical signs and symptoms by caretakers. Based on this review, further development of dengue algorithms is suggested, followed by recommendations for necessary research and for country-specific adaptations.