Mental health

Conventional and atypical antipsychotics and antidepressant (trazodone) for behavioural and psychological symptoms in people with dementia

[2012]

Recommendation(s)

Thioridazine, chlorpromazine or trazodone should not be used for the treatment of behavioural and psychological symptoms of dementia.
Strength of recommendation: STRONG
Quality of evidence: LOW

Haloperidol and atypical antipsychotics should not be used as first line management for behavioural and psychological symptoms of dementia. Where there is clear and imminent risk of harm with severe and distressing symptoms, the short term use of haloperidol or atypical antipsychotic medications may be considered, preferably with specialist inputs. To the extent possible, informed consent and agreement should be obtained from the person and carer with regard to balance of risk and benefit.
Strength of recommendation: STRONG
Quality of evidence: LOW

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