Patient safety

The research cycle: measuring harm

Classic studies in patient safety research

Research classics - measuring harm

Measuring what goes wrong in health-care involves counting how many patients are harmed or killed each year, and from which types of adverse events:

  • medication errors;
  • nosocomial infections;
  • wrong-site surgery, etc.

This is essential for raising awareness and setting research priorities.

  • Baker
    ppt, 963kb

    Retrospective chart review
    Baker GR, Norton PG, Flintoft V, et al. The Canadian adverse events study: the incidence of adverse events among hospital patients in Canada. CMAJ, 2004, 170:1678-1686.
  • Donchin
    ppt, 710kb

    Direct observation mixed methods approach
    Donchin Y, Gopher D, Olin M, et al. A look into the nature and causes of human errors in the intensive care unit. Qual. Saf. Health Care 2003, 12;143-147.
  • Gandhi
    ppt, 989kb

    Malpractice claims analysis
    Gandhi TK, Kachalia A, Thomas EJ, et al. Missed and delayed diagnoses in the ambulatory setting: a study of closed malpractice claims. Ann Intern Med. 2006;145:488-496.
  • Michel
    ppt, 886kb

    Mixed methods approach
    Michel P, Quenon JL, de Sarasqueta AM, Scemama O. Comparison of three methods for estimating rates of adverse events and rates of preventable adverse events in acute care hospitals. BMJ, 2004, 328; 199.
  • Seas
    ppt, 752kb

    Prospective cohort study
    Hernandez K, Ramos E, Seas C, Henostroza G, Gotuzzo E. Incidence of and risk factors for surgical-site infections in a Peruvian hospital. Infection Control and Hospital Epidemiology, 2005: 473-477.
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