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Research on neglected priority needs, including product R&D, evaluation in real life settings, and increasing access to new tools

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  • Diseases & topics

Helminths

Helminths are a broad range of organisms that include intestinal parasitic worms, (roundworms (Ascaris lumbricoides), whipworms (Trichuris trichiura), or hookworms (Necator americanus and Ancylostoma duodenale).

Infected people excrete helminth eggs in their faeces, which then contaminate the soil in areas with inadequate sanitation. Other people can then be infected by ingesting eggs or larvae in contaminated food, or through penetration of the skin by infective larvae in the soil (hookworms).

Infestation can cause morbidity, and sometimes death, by compromising nutritional status, affecting cognitive processes, inducing tissue reactions, such as granuloma, and provoking intestinal obstruction or rectal prolapse. Control of helminthiasis is based on drug treatment, improved sanitation and health education.

TDR related research

TDR supports research on this disease. Our work is being conducted in the following areas:

  • Schistosomiasis and soil-transmitted helminths

Latest news

  • A call for closer ties to communities
    5 March 2013
  • Pipeline grows for neglected diseases research and development (R&D)
    4 February 2013
  • Resolution on neglected tropical diseases to be recommended to WHO Health Assembly
    29 January 2013
  • WHO releases updates on targets to reduce NTDs
    16 January 2013
  • All news on helminths

TDR publications and articles

  • Research priorities for helminth infections
    16 October 2012
  • Changing Mindsets: Research Capacity strengthening in low and middle-income countries
    1 November 2010
  • A human rights-based approach to neglected tropical diseases
    20 February 2009
  • All publications on helminths
WHO/Henrietta Allen
A child of ~20 months being given a 500-mg mebendazole tablet crushed with water in Madagascar, 2006

Related WHO information

  • Information resources: intestinal worms
  • International travel and health
    Publication on travel risks, precautions and vaccination requirements
  • WHO Newsletter — "Action Against Worms"
    Partners for Parasite Control (PPC)

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