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Research on neglected priority needs, including product R&D, evaluation in real life settings, and increasing access to new tools

Developing research leadership through education, training, networks and quality management

Assessing global research needs and priorities, providing knowledge management and support for partner coordination

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  • Research
  • Malaria research
    • Community case management of malaria
    • Integrated community case management of childhood illness
    • Rapid diagnostic tests
    • Rectal artesunate testing and delivery
    • Safety of drugs in pregnancy
  • Neglected tropical diseases research
    • Chagas
    • Dengue
    • African trypanosomiasis
    • Onchocerciasis
    • Visceral leishmaniasis
    • Schistosomiasis and soil-transmitted helminths
  • Tuberculosis and HIV research
    • Shortening and simplifying TB treatment
    • TB/HIV research
    • Improving TB diagnostics
    • Enhancing health systems
  • Vectors, environment and society research
    • New methods and strategies
    • Community-based interventions
    • Environmental climate change impact
    • Enhancing access to control
    • Capacity building

Dengue

Dengue is a mosquito-borne infection of growing international public health importance, found in both tropical and sub-tropical regions, predominantly in urban and semi-urban areas. Severe dengue, a potentially lethal complication, affects most Asian and Latin-American countries and has become a leading cause of hospitalization and death among children in the region.

With no specific drug candidate for dengue treatment in sight, TDR supported an analysis of the dengue drug research portfolio which is available on the web (see below) to help identify candidates, facilitate interactions and promote R&D.

TDR research is also identifying how to improve classification and surveillance and outbreaks. A revised disease classification lead by TDR and WHO’s department of neglected tropical diseases is being tested and adopted in countries.

  • Dengue drug research portfolio
    pdf, 618kb
  • Dengue
  • Contact Dr Piero Olliaro

Latest news

  • New series on helminth infections R&D agenda
  • Dengue control support through eco-bio-social approach
  • A call for closer ties to communities
  • Pipeline grows for neglected diseases research and development (R&D)
  • VL elimination by 2015 on track with new research
  • Onchocerciasis can be eliminated with ivermectin
  • VL rapid diagnostics may be inadequate in Brazil and East Africa

Related links

  • African clinical trial site capacity available for other research
    pdf, 1.40Mb
  • Health Research Policy and Systems journal article: Empowering communities in combating river blindness
    May 2012

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Special Programme for Research and Training in Tropical Diseases (TDR)