Global Vaccine Safety

Immune overload

Committee reports

14 July 2006 - Immunogenic overload (from meeting of 6-7 June 2006)

Related links

Potential immunologic overload resulting from concomitant vaccination with too many antigens. Presented by David Goldblatt at the meeting of the Global Advisory Committee on Vaccine Safety held on 6-7 June 2006
pdf, 1.29Mb

References

Offit PA, Quarles J, Gerber M, Hackett C, et al. Addressing parents' concerns: do multiple vaccines overwhelm or weaken the infant's immune system? Paediatrics 2002; 109: 124-9. Abstract
Miller E et al. Bacterial infections, immune overload, and MMR vaccine. Arch Dis Child 2003;88: 222-3. Abstract
Hilton S, Petticrew M, Hunt K. Combined vaccines are like a sudden onslaught to the body's immune system': Parental concerns about vaccine 'overload' and 'immune-vulnerability'. Vaccine 2006 May 15;24(20):4321-7. Abstract

Page last updated: 14 July 2006
Page last reviewed: 15 February 2011

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