Global Vaccine Safety

WHO launches the Global Manual on Surveillance of Adverse Events Following Immunization

Monitoring of adverse events following immunization (AEFI) is an essential strategy for ensuring the safety of vaccines. This new manual provides guidance on setting-up AEFI surveillance systems with standardized methodologies and tools. It addresses the investigation of AEFI, how to analyze surveillance data, causality assessment and how to respond to serious AEFI, including communication. It also includes a description of the most common vaccine reactions provides references to the most recent references in vaccine pharmacovigilance. The manual is currently being translated in French and Spanish.

Focus on Africa - Vaccine safety capacity building in Tanzania

11 – 14 August 2014, Bagamoyo town, Tanzania.

A four-day capacity building workshop on AEFI surveillance and response was organized in Bagamoyo town, Tanzania from 11 – 14 August 2014. As Tanzania is preparing for mass immunization campaigns with multiple vaccines and drugs, the workshop was the opportunity to clarify the flow of vaccine safety information, roles and responsibilities with 21 national participants. The didactic sessions and group work were modelled on the WHO advanced course for causality assessment in vaccine pharmacovigilance.

In addition, 6 international participants from Ethiopia, Ghana, Kenya, Malawi, Nigeria, and Zimbabwe attended the meeting. Similar workshops will be conducted in their respective countries as part of a regional effort to strengthen national capacity for vaccine safety.

East Mediterranean Regional Workshop on Causality Assessment of AEFI

Twenty nine health professionals from Egypt, Iran, Jordan, Morocco, Oman, Pakistan, Saudi Arabia, Sudan and Tunisia participated in the Regional Workshop on Revised WHO Methodology for Assessment of Causality for Adverse Events Following Immunization (AEFI) held in Muscat from 23-26 June 2014. The workshop focused on providing “hands on” participatory training on AEFI causality assessment using cases from participating countries. The meeting was coordinated by WHO and an Associate Professor of Pediatrics from Tehran University of Medical Sciences. The meeting was also an opportunity for countries to draft their work plans for sustainable vaccine safety activities.

The latest version of the GVSI portfolio of activities available online

The latest GVSI portfolio of activities is now available. You will be able to glance through a number of new projects supported by various stakeholders that have recently join the effort. The latest tools and intelligence generated within the framework of the Initiative and offered to Member States to assist them in strengthening their vaccine pharmacovigilance systems include a template of AEFI notification form, an updated template of AEFI investigation form, the WHO vaccine reaction rates information sheets, a tool for assessing AEFI causality with its manual and aide-memoire, the newly launched Vaccine Pharmacovigilance Toolkit, a Brighton Collaboration Narcolepsy Case Definition etc.

GVSI highlights