Determination of equivalence for public health pesticides and pesticide products
Report of a WHO consultation, Geneva, Switzerland 17–18 October 2016
On 17–18 October 2016 the Department of Control of Neglected Tropical Diseases, the Global Malaria Programme and the Prequalification Team of the World Health Organization (WHO) convened an expert consultation with the following objectives:
- to discuss the outcomes of a WHO informational session on determination of equivalence for pesticide-based vector control products held on 1–2 February 2016;
- to further understand the perspectives of pesticide manufacturers on the current equivalence criteria and procedures established jointly by the Food and Agriculture Organization of the United Nations (FAO) and WHO; and
- to advise on the FAO/WHO criteria, procedures and data requirements for determination of equivalence for public health pesticide products.
The meeting reviewed the current WHO parameters and criteria for the evaluation of public health pesticide products within four main categories for which WHO has long established their public health value, namely: long-lasting insecticidal nets (LLINs), insecticides for indoor residual spraying (IRS), mosquito larvicides, and insecticides for space spraying. The meeting discussed the FAO perspectives on equivalent pesticides for agricultural use, procedures for listing equivalent medicines under prequalification by WHO, and determination of equivalence from a country-level regulatory perspective in Chile, Kenya, India, the European Union and the United States Environmental Protection Agency. The perspectives of both innovator industries and generic industries were considered during the open session. The closed meeting scrutinized current WHO procedures and criteria for determination of equivalence for generic public health pesticides.