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Situation and trends: 630 000 [490 000−820 000] people died of HIV-related illnesses worldwide in 2024. Expanded access to antiretroviral therapy (ART) and a declining incidence of HIV infections have led to a steep fall globally in the number of adults and children dying from HIV-related causes. The estimated 630 000 [490 000−820 000] people dying from HIV globally in 2024 were 70% fewer than in 2004 (the peak) and 54%(1) fewer than in 2010 in spite of a period of substantial population growth in many high burden countries. Nevertheless, there is no room for complacency. Countries need to live up to their commitment to end the AIDS epidemic as a public health threat by 2030 -- a target included in the 2030 Agenda for Sustainable Development adopted by the United Nations General Assembly in September 2015. The drop in HIV-related mortality is especially evident in the regions with the greatest burden of HIV infection, including the WHO African Region, home to over 61% of people dying from HIV-related causes in 2024. An estimated 380 000 [310 000−490 000] people died in the African Region from HIV-related causes in 2024, which indicates that mortality has dropped by almost 59% since 2010. (1) Percentage change in HIV estimates was calculated from unrounded estimates in the corresponding text.
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