Hepatitis - diagnosis coverage of chronic hepatitis (HBV and HCV) among total infected
Topic:
Hepatitis, burden of disease, hepatitis response
Rationale:
Proportion of people with chronic hepatitis B and C who know their infection status measures the entry point to the continuum of care.
Definition:
• Proportion of people with chronic hepatitis B (HBsAg positive) who have been diagnosed
• Proportion of people with chronic hepatitis C who have been diagnosed (HCV RNA positive or HCV core antigen positive) including those cured
Disaggregation:
By country and WHO region
Method of measurement
Counting persons reported with chronic infection and dividing this number by the estimated size of the population infected. In that case, the numerator is the number of persons reported with chronic HBV and/or HCV infection from health-care facilities (case reporting) and/or laboratories, while the denominator is the estimated size of the population infected (modelled or estimated from a biomarker survey). For chronic HCV the numerator includes those with resolved infection (cured or naturally cleared) . This is intended to reflect the historical testing effort and coverage. Those with re-infection are included but counted once. Whereas, the denominator includes all total HCV infections (all ages) since 2015
Method of estimation:
Modelling can be used alongside available routine programme data to estimate the size of the population infected. For example, prevalence data obtained from a population survey conducted at one time may be used estimate prevalence at a more recent time. Such models need to consider relevant input parameters such as the number of people treated and cured over time, hepatitis C incidence and deaths (liver-related deaths and other causes of death in the general population).
Method of estimation of global and regional aggregates:
Estimates are also produced at global level and for WHO regions
Preferred data sources:
Surveillance systems
Health facility data
Information may be sourced from specific programme or clinical patient monitoring tools (electronic or paper medical records), hepatitis testing records, laboratory registers, logbooks and reporting forms at the facility and community levels
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