Currently circulating variants of concern (VOCs) as of 15 March 2023
Note: To better reflect the current variant landscape, which is dominated by Omicron descendent lineages, WHO updated its tracking system and working definitions of VOCs and VOIs on 15 March 2023.
Currently circulating variants of interest (VOIs) (as of 2 December 2024)
| Pango lineage | Next strain clade | Genetic features | Earliest documented samples | Date of designation and risk assessments |
JN.1#
| 24A | BA.2.86 + S:L455S | 25-08-2023 | 18-12-2023 JN.1 Initial Risk Evaluation 18 December 2023 JN.1 Updated Risk Evaluation 9 February 2024 JN.1 Updated Risk Evaluation 15 April 2024
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#Excludes JN.1 sublineages listed as VUMs below.
Currently circulating variants under monitoring (VUMs) (as of 4 Sept. 2025)
| Pango lineage | Next strain clade | Genetic features | Earliest documented samples | Date of designation and risk assessments |
| KP.3.1.1 | 24E | KP.3 + S:S31- | 27-03-2024 | 19-07-2024 |
| XEC | 24F | JN.1 + S:T22N, S:F59S, S:F456L, S:Q493E, S:V1104L | 26-06-2024 | 24-09-2024 XEC Initial Risk Evaluation 09 December 2024 |
| LP.8.1 | 25A | JN1 + S:S31-, S:F186L, S:R190S, S:R346T, S:V445R, S:F456L, S:Q493E, S:K1086R, S:V1104L | 01-07-2024 | 24-01-2025 LP.8.1 Initial Risk Evaluation 03 February 2025 |
| NB.1.8.1 | 25B | JN1 + S:T22N, S:F59S, S:G184S,S:A435S, S:F456L, S:T478I, S:Q493E | 22-01-2025 | 23-05-2025 NB.1.8.1 Initial Risk Evaluation 23 May 2025 |
| XFG | 25C | JN1 + S:T22N, S:S31P, S:K182R, S:R190S, S:R346T, S:K444R, S:V445R, S:F456L, S:N487D, S:Q493E, S:T572I | 27-01-2025 | 25-06-2025 XFG Initial Risk Evaluation 25 June 2025 |
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