Currently circulating variants of concern (VOCs) as of 15 March 2023

Note: To better reflect the current variant landscape, which is dominated by Omicron descendent lineages, WHO updated its tracking system and working definitions of VOCs and VOIs on 15 March 2023.

Currently circulating variants of interest (VOIs) (as of 2 December 2024)

Pango lineageNext strain cladeGenetic featuresEarliest documented samplesDate of designation and risk assessments

 

JN.1#

 

24A

BA.2.86 + S:L455S

25-08-2023

18-12-2023

JN.1 Initial Risk Evaluation 18 December 2023

JN.1 Updated Risk Evaluation 9 February 2024

JN.1 Updated Risk Evaluation 15 April 2024

 

#Excludes JN.1 sublineages listed as VUMs below.

Currently circulating variants under monitoring (VUMs) (as of 5 Dec. 2025)

Pango lineageNext strain cladeGenetic featuresEarliest documented samplesDate of designation and risk assessments
KP.3.1.124EKP.3 + S:S31-27-03-202419-07-2024
LP.8.125AJN1 + S:S31-, S:F186L, S:R190S, S:R346T, S:V445R, S:F456L, S:Q493E, S:K1086R, S:V1104L01-07-202424-01-2025  LP.8.1 Initial Risk Evaluation 03 February 2025 
NB.1.8.125BJN1 + S:T22N, S:F59S, S:G184S,S:A435S, S:F456L, S:T478I, S:Q493E 22-01-202523-05-2025 NB.1.8.1 Initial Risk Evaluation 23 May 2025
XFG25CJN1 + S:T22N, S:S31P, S:K182R, S:R190S, S:R346T, S:K444R, S:V445R, S:F456L, S:N487D, S:Q493E, S:T572I27-01-202525-06-2025 XFG Initial Risk Evaluation 25 June 2025
BA.3.2 Relative to Index:
P9L, R21T, P26L, A67V, H69-, V70-, T95I, I101T, C136-, N137-, D138-, P139-, F140-, L141-, G142-, V143-, Y144-, Y145-, H146-, K147-, F157S, N164K, S172F, K187T, N211-, L212I, A243-, L244-, P251S, I326V, G339Y, A348P, S371F, S373P, S375F, R403K, D405N, R408S, K417N, A435S, N440R, V445A, G446D, L452W, N460K, S477N, T478N, E484K, G496S, Q498R, N501Y , K529N, E554D, E583D, D614G, H625R, N641K, V642G, E654K, H655Y , N679R, P681R, A688D, S704L, N764K, K795T, D796Y , A852K, S939F, Q954H, N969K, P1162R, D1184E		22-11-2024

05-12-2025

BA.3.2 Initial Risk Evaluation 05 December 2025