Hepatitis B vaccination and chronic fatigue syndrome

The Committee considered the possible association between hepatitis B vaccination and chronic fatigue syndrome that had been reported in Canada. A thorough literature review of the issue was commissioned. The review revealed that only 3 case-control studies had examined the issue and that all 3 studies had limitations. The Committee concluded that, based on the evidence available, there are no grounds to support the association.

Full report of GACVS meeting of 1-2 December 2005, published in the WHO Weekly Epidemiological Record on 13 January 2006