©WHO/Yoshi Shimizu
A researcher dissects a mosquito under the microscope at the Malaria Research Centre in Khanh Vinh district
© Credits

Research

    Overview

    Research is indispensable for resolving public health challenges – whether it be tackling diseases of poverty, responding to rise of chronic diseases,  or ensuring that mothers have access to safe delivery practices.

    Likewise, shared vulnerability to global threats, such as severe acute respiratory syndrome, Ebola virus disease, Zika virus and avian influenza has mobilized global research efforts in support of enhancing capacity for preparedness and response. Research is strengthening surveillance, rapid diagnostics and development of vaccines and medicines.

    Public-private partnerships and other innovative mechanisms for research are concentrating on neglected diseases in order to stimulate the development of vaccines, drugs and diagnostics where market forces alone are insufficient.

    Research for health spans 5 generic areas of activity:

    • measuring the magnitude and distribution of the health problem;
    • understanding the diverse causes or the determinants of the problem, whether they are due to biological, behavioural, social or environmental factors;
    • developing solutions or interventions that will help to prevent or mitigate the problem;
    • implementing or delivering solutions through policies and programmes; and
    • evaluating the impact of these solutions on the level and distribution of the problem.

     

    WHO response

    High-quality research is essential to fulfilling WHO’s mandate for the attainment by all peoples of the highest possible level of health. One of the Organization’s core functions is to set international norms, standards and guidelines, including setting international standards for research.

    Under the “WHO strategy on research for health”, the Organization works to identify research priorities, and promote and conduct research with the following 4 goals:

    • Capacity - build capacity to strengthen health research systems within Member States.
      • Priorities - support the setting of research priorities that meet health needs particularly in low- and middle-income countries.
      • Standards - develop an enabling environment for research through the creation of norms and standards for good research practice.
      • Translation - ensure quality evidence is turned into affordable health technologies and evidence-informed policy.
      WHO’s research activities also include strengthening the culture of research for evidence-based decision-making within the Organization so that research informs our technical activities, policy decisions and recommendations.

       

      News

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      Publications

      Cancer research and development landscape: overview of 1999-2022 period 

      Despite significant progress in therapeutic development, cancer is still associated with a substantial global disease burden, which is projected...

      Landscape analysis of the opportunities and challenges for neurotechnology in global health

      This report provides a detailed examination of the current landscape of neurotechnology, specifically exploring both its potential benefits and challenges...

      WHO Technical Advisory Group on the responsible use of the life sciences and dual-use research: report of the meeting, 22 January 2025

      The World Health Organization (WHO) Technical Advisory Group on the Responsible Use of the Life Sciences and Dual-Use Research (TAG-RULS DUR) was established...

      Our work

      Optimizing research and development processes for accelerated access to health products

      Optimizing research and development processes for accelerated access to health products

      WHO / Colin Cosier
      © Credits

      Overview

      Access to appropriate health products such as vaccines, diagnostics, medicines and vector control products is essential to achieve WHO’s mission to ensure universal health coverage, respond to global health threats and promote a healthier population. Promoting research and development of innovative products and facilitating their introduction are vital activities to ensure the global community can address unmet health needs. 

      To this end, WHO has developed an optimized process that allows WHO activities in research prioritization, health product development advice, WHO policy guidance production, product assessment through prequalification, and support to implementation in countries to become linked, efficient, and coherent, with consequent increased impact on health outcomes. The ultimate goal of the process is to ensure the development of health products that address global health needs and to accelerate implementation and uptake in countries.