List of substances scheduled for new compounds, periodic reevaluation, follow-up evaluation or new uses and request for data
Issued December 2025
Attached is the list of substances (Annex 1) scheduled for evaluation at the 2026 Joint FAO/WHO Meeting on Pesticide Residues (JMPR). This list has been prepared by the Joint FAO/WHO Secretariat of the Meeting and is based on recommendations of the Codex Committee on Pesticide Residues (CCPR), previous Expert Meeting, and direct requests from governments, other interested organizations, and producers of substances that have been evaluated previously.
Submission of data
Annex 1 lists the pesticides to be considered at the meeting. Governments, interested organizations, producers of these chemicals, and individuals are invited to submit data for the toxicological and the residues evaluations of the compounds listed.
The submitted data may be published or unpublished and should contain detailed reports of laboratory studies, including individual animal data. Reference to relevant published studies should also be provided, where applicable.
In addition to original data mentioned above, the submission of existing regulatory dossiers as well as summaries in the form of monographs is helpful and is therefore strongly recommended.
Unpublished confidential studies that are submitted will be safeguarded and will be used only for evaluation purposes by JMPR. Summaries of the studies will be published by FAO and WHO after the meetings in the form of residue and toxicological monographs.
Should you wish for your data submission to be made available to other Joint FAO/WHO scientific committees than JMPR please state this explicitly in a cover letter accompanying your submission with clear references to the extent of the data package that can be shared.
The secretariats of JMPR at FAO and WHO encourage electronic submissions. Such data should be presented preferably using standard word processing or document formats.
I. Toxicological Evaluation
The submission of data on those compounds listed in Annex 1 for toxicological evaluation is requested before
19 January 2026
Toxicological data
Data relevant to the toxicological evaluations of the substances on the agenda include the results of studies on:
- Biochemical data: metabolism and pharmacokinetic studies, effects on enzymes and other biochemical parameters;
- Toxicological studies: acute toxicity, short-term toxicity, long-term toxicity/carcinogenicity; genotoxicity; reproductive studies;
- Epidemiological, occupational health and other such observational studies of the potential health effects of human exposures
- Special studies designed to investigate specific effects of the compound, such as neurotoxicity, immune responses, mechanism of toxicity, or macromolecular binding.
- Data, studies or reasoned argument to determine the toxicological relevance of pesticide metabolites and degradates: This should include within the toxicological dossier a summary table for the occurrence of parent compounds, metabolites and degradates in various crops and animals. Where metabolites may be formed by alternate pathways in test species, evidence should be provided for the extent of exposure to intermediate metabolite(s), if these could be toxicologically relevant.
- For metabolites and degradates for which experimental data are not available, results of in silico predictive models for genotoxicity i.e. (quantitative) structure activity relationships (Q)SAR, and identification of structural alerts. A clear indication of the models used, their rationale and limitations, as well as reasoned read-across should also be included.
- Studies designed to evaluate the possibility that residues of the compound might have an adverse effect on the microbial ecology of the human intestinal tract and/or an increase in anti-bacterial resistance (AMR).
- Data from new molecular, cell and computer-based approaches: There has been great interest in the development of new mechanistic-based approaches. It is the opinion of JMPR that scientific developments and understanding are not sufficient at this time to enable the replacement of in vivo testing with in vitro methods to predict hazards and potency for systemic toxicities. However, new approaches can be used to complement traditional testing. In addition, JMPR offers to evaluate without prejudice, in parallel, any data generated using emerging methods that in the view of sponsors could substitute for information obtained using conventional testing methods (see Report of 2012 and 2013 JMPR).
For more information, please refer to the Pesticide residues in food: guidance document for WHO monographers and reviewers.
NOTE 1: for compounds scheduled for evaluation of toxicity, please note that the full toxicological data package is required. Data submission should focus on all data relevant to determine the potential for public health concern. This includes mainly acute and short-term toxicity studies, but also special studies such as neurotoxicity if relevant, or studies on the mechanism of action.
NOTE 2: For compounds listed for new uses, only data not previously submitted to JMPR should be collected.
All data should be sent to:
Attention: Ms. Juliana De Oliveira Mota
Department of Nutrition and Food Safety
World Health Organization
Avenue Appia
1211 Geneva 27
Switzerland
Telephone: (+41) (0)22 791 36 97
E-mail: jmpr@who.int
II. Residue Evaluation
The submission of data on those compounds listed in Annex 1 for residue evaluation are requested before.
1 February 2026
For details on data submission, please refer to the FAO Manual on the Submission and Evaluation of Pesticide Residues Data published at the FAO website: Pesticide residues, third edition
All data should be sent directly to the FAO Panel Member assigned to review the compound and only an electronic copy to FAO.
Attention: Mr Guibiao Ye
Plant Production and Protection Division
Food and Agriculture Organization
Viale delle Terme di Caracalla
00100 Rome
Italy
Telephone: (+39) 06 570 53506
E-mail: guibiao.ye@fao.org
For electronic data submissions to WHO, a system of direct upload of data through a link to a folder on the WHO SharePoint has been introduced. Please contact the secretariat for further instructions.
This call for data is available at both the FAO and WHO web sites:
FAO: FAO/WHO Joint Meeting on Pesticide Residues (JMPR)
WHO: Joint FAO/WHO Meeting on Pesticide Residues (JMPR)
Annex 1
List of substances scheduled for evaluation or re-evaluation
Previous reports and monographs should be consulted to obtain background information on the previous evaluations. For details please refer to
FAO/WHO Joint Meeting on Pesticide Residues (JMPR)
RESIDUE EVALUATIONS | TOXICOLOGICAL EVALUATIONS |
|---|---|
New Compounds | New Compounds |
Fenmezoditiaz | Fenmezoditiaz |
Metyétetraprole | Metyétetraprole |
Metyétetraprole | |
Dimpropyridaz (addtional data, if any) (carry over from 2025 JMPR) | Dimpropyridaz (addtional data on metabolites if any) |
Fluazinam (306) (additional data, if any) (carry over from 2023 after finalization of toxicological evaluation in 2024.) | Fluazinam (306) (addtional data on metabolites if any) |
Ipflufenoquin (additional data, if any) (carry over from 2025 JMPR) | Ipflufenoquin (addtional data on metabolites if any) |
Spidoxamat (additional data, if any) (carry over from 2025 JMPR) | Spidoxamat (addtional data on metabolites if any) |
Periodic Reevaluations | Periodic Reevaluations |
Indoxacarb (216) | Indoxacarb (216) |
Maleic hydrazide (102) | Maleic hydrazide (102) |
Captan (107) | Captan (107) |
Permethrin (carry over from 2023 JMPR after finalization of toxicological evaluation in 2025) | |
Malathion (carry over from 2025 JMPR) | Malathion (additional data, if any) |
New uses and other evaluations | Follow up evaluationsa |
Bixafen (262) | |
Cyclobutrifluram |
|
Dinotefuran (carry over from call for data 2025) | |
Dimethoate (27) | |
Etofenprox (184) | |
Flonicamid (and its metabolite Flumetnicam) | |
Florylpicoxamid (332) | |
Fluazaindolizine (327) |
|
Fludioxonil (211) | |
Fluopyram (243) |
|
Fluoxapiprolin (999) | |
| Fluoyradifurone (285) |
|
Flutriafol (248) | |
Fosetyl-Al (302) | |
Gllyphosale (158) | |
Isocycloseram (addition crops carry over from 2024 JMPR) |
|
Isotianil (999) | |
Iambda-cyhalothrin | |
Metalaxyl (138) / Metalaxyl-M (212) |
|
Oxathiapiprolin | Oxathiapiprolin |
Phosphonic acid (301) | |
Spiropidion (323) | |
Sulfoxaflor (252) |
|
Tetraniliprole (324) | |
Trifloxystrobin (213) | |
Chlorantraniliprole (230, reserved) |
|
Tebufenozide (196, reserved) |
|
[a] For all new uses to be evaluated for residues, available toxicological data which were not submitted previously should be provided to WHO.