Tests for glucose-6-phosphate dehydrogenase activity

Overview

Target product profiles (TPPs) as key tools to incentivize and guide the development of urgently needed health products. The TPPs published here describe the characteristics of new types of diagnostics to measure glucose-6-phosphate dehydrogenase (G6PD) activity. These diagnostics are expected to facilitate safe and effective treatment with 8-aminoquinolines to prevent Plasmodium vivax relapse and reduce onward malaria transmission. They may also have other applications, such as screening neonates for G6PD deficiency, investigating acute haemolytic anaemia and genetic counselling. The target audience consists of all those working to evaluate assays or to develop new assays for G6PD testing.