Handbook for Adapting and Implementing Evidence-Informed Guidelines. Second Edition

Overview

The Pan American Health Organization presents this manual aimed at government entities, health authorities public, health professionals, patients and other people and institutions interested in the development of guidelines informed by evidence. Its objective is to present the political and methodological strategies for the creation and strengthening national production program guidelines in the Region of the Americas. In this second edition the guidelines process is reviewed according to the latest version of the method classification of assessment, preparation and evaluation of recommendations (known as GRADE). The formulation of recommendations, the construction of evidence profiles, and creation of frameworks for moving from evidence to decisions present new conceptual frameworks for the creation or strengthening of guideline programs (logical model of the operation of the program, steps for its institutionalization and challenges for the government entities), and the key aspects of the process of implementation of guidelines developed by countries or health institutions of the Region (barriers, strategies and implementation facilitators, and indicators).