WHO Living guideline: Drugs to prevent COVID-19
Interim guidance
Overview
The
WHO Living guideline: Drugs to prevent COVID-19 contains the
Organization’s most up-to-date recommendations for the use of drugs to prevent
COVID-19. The latest version of this living guideline is available in
pdf format (via the ‘Download’ button) and via an online platform, and is updated regularly as new evidence emerges.
Current
use of drugs to prevent COVID-19 is variable, there is a high level of
uncertainty regarding the evidence-base, and there are numerous randomized
clinical trials of many different drugs underway to inform practice.
This
first version of the WHO COVID-19 prophylaxis guideline includes one
recommendation on hydroxychloroquine which was informed by a living network
meta-analysis (LNMA) of six trials.
The
WHO Living guideline: Drugs to prevent COVID-19 currently includes a:
• strong recommendation
against administering hydroxychloroquine prophylaxis to individuals who do not have COVID-19 (first version, published 2
March 2021, access as pdf or via online platform).
Guidelines regarding the use of drugs to treat (rather than prevent) COVID-19 are included in a separate WHO document, Therapeutics and COVID-19: living guideline, that can via an online platform and in pdf format (or click ‘PDF’ in top right corner of online platform).
Guidelines regarding the clinical management of COVID-19 patients are included in a further document, COVID-19 Clinical management: Living guideline, that can be accessed via an online platform and in pdf format (or click ‘PDF’ in top right corner of online platform).
