Ethical considerations for use of unregistered interventions for Ebola virus disease

Overview

West Africa is experiencing the largest, most severe, most complex outbreak of Ebola virus disease in history. On 11 August 2014, WHO convened a consultation to consider and assess the ethical implications for clinical decision-­making of use of unregistered interventions that have shown promising results in the laboratory and in animal models but that have not yet been evaluated for safety and efficacy in humans.