Malaria vaccine: WHO position paper – March 2022
Weekly Epidemiological Record, 2022, 97 (09): 60 - 78

Overview
This position paper supersedes the 2016 publication,
“Malaria vaccine: WHO position paper-2016". It includes
the updated WHO recommendations on the wider use
of the RTS,S/AS01 vaccine for the reduction of malaria
morbidity and mortality in children living in areas of
moderate to high malaria transmission. It also incorporates findings from the evaluation of the WHO-coordinated Malaria Vaccine Implementation Programme
(MVIP), recommended by SAGE and MPAG in 2015, and
from additional studies since 2015.
This paper does not
include findings on vaccine efficacy in infants first
vaccinated at 6–12 weeks of age. Because of the lower
vaccine efficacy observed in this age category, WHO did
not recommend pilot implementation or RTS,S/AS01
vaccine| introduction for these young infants. Recommendations on the use of RTS,S/AS01 vaccine were
discussed by SAGE and MPAG during a joint session in
October 2021.