Smallpox abstract: 2006 report on support for development of second and third generation smallpox vaccines

The WHO Collaborating Center for Smallpox and other Poxviruses at the Centers for Disease Control and Prevention Atlanta, GA

Overview

Vaccine trials are underway to access the safety and efficacy of novel second generation smallpox vaccines in human subjects. As part of the assessment, samples were submitted to the Centers for Disease Control and Prevention for testing the ability to neutralize Variola virus in vitro. Plaque reduction and neutralization assays (PRNTs) were performed on trial sera against a Variola strain originally isolated from Bangladesh.

 

WHO Team
Communicable Diseases
Number of pages
1