Proposed framework for policy decision on RTS,S/AS01 Malaria vaccine

The intention of this proposed Framework for Policy Decision (FPD) document is to provide relevant background and information and to present the Working Group recommendations to the World Health Organization (WHO)’s Strategic Advisory Group of Experts (SAGE) on Immunization and the Malaria Policy Advisory Committee (MPAC) on how the data generated by the Malaria Vaccine Implementation Programme (MVIP) can be used, as they become available, to inform policy decisions. The Framework will provide an opportunity for discussion and alignment of views prior to key time points for recommendations by the SAGE and MPAC to WHO regarding the broader use of the RTS,S/AS01 malaria vaccine.

To develop the Framework, a Working Group was established of representatives from WHO advisory bodies involved in malaria vaccine policy decision making. They reviewed data and information that led to the 2016 WHO malaria vaccine position paper, and data and information that has emerged since then. Background was provided on the MVIP, along with a summary of policy precedents on malaria interventions and prior SAGE policy decisions on vaccines, to facilitate Working Group discussions around a series of FPD key questions.