The Active Prevention and Treatment of Maternal Sepsis (APT-Sepsis)

Overview

Objectives: A cluster randomised, hybrid implementation effectiveness trial, to improve prevention and management of maternal sepsis in health care facilities in Malawi and Uganda

The APT-Sepsis intervention brings together evidence-based practice to address these issues via an integrated programme with three interventional domains and an implementation strategy. This project will evaluate if implementation of the APT-Sepsis programme is effective at reducing infection related maternal mortality and severe morbidity through a cluster randomised trial in 60 health care facilities in Malawi and Uganda. We will also conduct a rigorous process evaluation to understand the implementation of the programme and will determine its cost effectiveness.