Immunization Analysis and Insights
The Immunization Analysis & Insights Unit is a data hub and analytics engine for immunization data and performs analytics. The unit supports the work of other technical units within the department of Immunization, Vaccines and Biologicals (IVB) and drives innovation in data quality and use in countries. It also has responsibility for IVB’s global work on VPD surveillance and generating data and evidence on the public health and economic impact of vaccines.

Annexes to the Laboratory Manual Homepage

The annexes provide basic test method details or guidance documents to augment the material in the laboratory manual. The annex materials and protocols are not intended to provide laboratories with a standard operating protocol (SOP) as is, but may serve as a template for each individual laboratory to develop SOPs, and to stay current with new techniques as appropriate according to availability and resources.

The inclusion of reagents and products from specific manufacturers does not constitute an endorsement by the WHO or the GMRLN.

The documents are organized by subject matter into groups designated by a letter (A-F) and a number. Each annex in the list is assigned a consecutive number. If a document is superseded by a revised version, the new version will have a numeric extension. For example, if a revised version of an existing document named Annex B5 becomes available, the revised document will replace the original document and will be referred to as Annex B5.2.

New protocols will be added to the appropriate group with the next consecutive number at the end of the existing list.

 

The annex groups are organized according to subject matter described below. Click on the annex group below to navigate to the page with the directory (list) of the individual protocols (and links to pdfs) within the annex group.

 

Group A Annex Directory: Specimen collection, transport, and processing

Group B Annex Directory: Protocols and documents for specimen testing (case confirmation)

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Group C Annex Directory: Protocols and documents for sequencing and genetic analysis

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Group D Annex Directory: Resources and information related to laboratory quality assessment or management

  • Annex D1. Levey–Jennings control charts
  • Annex D2. Supplemental information for optimal laboratory design
  • Annex D3. Trouble shooting guide for IgM EIAs [Pending]
  • Annex D4. Recommendations for the evaluation of EIAs for IgM detection [Pending]
  • Annex D5. Verification for new IgM EIAs [Pending]
  • Annex D6. Accreditation checklists [Pending]:
    • Annex D6 - Part 1: Accreditation checklist Section 1 GENERAL
    • Annex D6 - Part 2: Accreditation checklist Section 2 SEROLOGY
    • Annex D6 - Part 3: Accreditation checklist Section 3 MOLECULAR
    • Annex D6 - Part 4: Accreditation checklist Section 4 VIRUS ISOLATION
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Group E Annex Directory: Techniques for additional characterization of specimens and cases

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Group F Annex Directory: Methods for measurement of population immunity

  • Annex F1. Mixture modeling [Pending]
  • Annex F2. Limitations and recommendations for measurement of measles and rubella IgG [Pending]
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For inquiries, please contact:

Dr. Mick N. Mulders, Scientist

Coordinator Global VPD Laboratory Networks

Expanded Programme on Immunization (EPI)

Department of Immunization, Vaccines & Biologicals (IVB)

Universal Health Coverage/Lifecourse Division (UHC/LC)

Mail: muldersm@who.int