Immunization Analysis and Insights
The Immunization Analysis & Insights Unit is a data hub and analytics engine for immunization data and performs analytics. The unit supports the work of other technical units within the department of Immunization, Vaccines and Biologicals (IVB) and drives innovation in data quality and use in countries. It also has responsibility for IVB’s global work on VPD surveillance and generating data and evidence on the public health and economic impact of vaccines.

Vaccine Preventable Diseases Surveillance Standards

Description

The purpose of this document is to provide World Health Organization (WHO)-recommended standards for conducting surveillance for vaccine preventable diseases (VPDs). VPD surveillance provides vital information to help countries understand disease burden and epidemiology to inform vaccine policy and strategy. This document is intended to provide a set of standards that countries should consider in establishing and improving existing VPD surveillance. Countries may adapt these standards based on local epidemiology, policy, disease control objectives and strategies. While the primary audiences of this document are country programme managers, it is important to recognize that standardized global surveillance data are useful for developing global vaccination policy.
These guidelines are not intended to be comprehensive for all aspects of VPDs. This document does not include step-by-step surveillance protocols, detailed laboratory methods, templates for line lists or databases, recommendations for monitoring adverse events following immunization or guidance on vaccination coverage surveys. In addition, details on routine immunization schedules will not be given here but may be found on the WHO website.

French and Russian versions available via the "Learn more" button.

WHO_SurveillanceVaccinePreventable_01_Overview_R2_page1

This document provides World Health Organization (WHO)-recommended standards for conducting surveillance for vaccine-preventable diseases (VPDs). VPD...

WHO_SurveillanceVaccinePreventable_02_Cholera_R2_page1

Cholera is a diarrhoeal disease caused by toxigenic serogroups of the bacterium Vibrio cholerae, which can cause rapid dehydration and death. Cholera...

WHO_SurveillanceVaccinePreventable_04_Diphtheria_R2_page1

Diphtheria is caused by Corynebacterium species, mostly by toxin-producing Corynebacterium diphtheriae and rarely by toxin-producing strains of C....

WHO_SurveillanceVaccinePreventable_06_HepA_R2_page1

The hepatitis A virus (HAV) is transmitted primarily via the faecal/oral route either through ingestion of contaminated food and water or through direct...

WHO_SurveillanceVaccinePreventable_07_HepB_R2_page1

Hepatitis B virus (HBV) is transmitted by exposure of  mucosal membranes or non-intact skin to infected blood  or other body fluids....

WHO_SurveillanceVaccinePreventable_08_HumanPapillomavirus_R2_page1

Human papillomaviruses (HPV) are the most common sexually transmitted infection. Although the majority of infections do not cause illness, persistent...

WHO_SurveillanceVaccinePreventable_05_HaemophilusInfluenzae_R2_page1

The bacteria Haemophilus influenzae type b (Hib) was the leading cause of non-epidemic bacterial meningitis worldwide in children prior to the introduction...

WHO_SurveillanceVaccinePreventable_09_Influenza_R2_page1

Influenza viruses are orthomyxoviruses that cause acute respiratory illness, ranging from mild febrile illness accompanied by body aches, cough and...

WHO_SurveillanceVaccinePreventable_10_JapaneseEncephalitis_R2_page1

Japanese encephalitis ( JE) is one of the most common encephalitides worldwide, with an estimated 68 000 cases and 13 20–600 400 deaths annually...

WHO_SurveillanceVaccinePreventable_11_Measles_R2_page1

Measles is one of the most contagious diseases for humans. It is caused by a paramyxovirus virus, manifesting as a febrile rash illness. The incubation...

WHO_SurveillanceVaccinePreventable_12_Meningococcus_R2_page1

Neisseria meningitidis (Nm) is a gram-negative bacterium that usually resides harmlessly in the human pharynx. Under certain conditions, asymptomatic...

WHO_SurveillanceVaccinePreventable_13_Mumps_R2_page1

Mumps, caused by a paramyxovirus, is generally a mild disease with fever, headache and swelling of the salivary glands (parotitis); however, complications...

WHO_SurveillanceVaccinePreventable_16_Pertussis_R2_page1

Pertussis (whooping cough), caused by Bordetella pertussis, is endemic in all countries. Globally, it is estimated that there were 24.1 million pertussis...

WHO_SurveillanceVaccinePreventable_17_Pneumococcus_R2_page1

The bacteria Streptococcus pneumoniae (pneumococcus) is the most frequent cause of severe pneumonia and pneumonia deaths worldwide. Pneumococci frequently asymptomatically...

WHO_SurveillanceVaccinePreventable_18_Polio_R2_page1

Polioviruses are human enteroviruses with serotypes 1, 2 or 3. The incubation period is usually 7–10 days (range 4–35 days). Most people...

WHO_SurveillanceVaccinePreventable_19_Rotavirus_R2_page1

Rotavirus, a member of the reovirus family, causes watery diarrhoea, vomiting and severe dehydration in young children. Rotavirus is common, accounting...

WHO_SurveillanceVaccinePreventable_20_Rubella_R2_page1

Rubella is an acute viral disease traditionally affecting susceptible children and young adults. Its public health importance is due mainly to the...

WHO_SurveillanceVaccinePreventable_03_CRS_R2_page1

Rubella is an acute viral disease often affecting susceptible children and young adults worldwide. Although it causes only a mild clinical illness...

WHO_SurveillanceVaccinePreventable_14_NeonatalTetanus_R2_page1

The World Health Organization (WHO) estimated that there were 34 000 neonatal tetanus (NT) deaths worldwide in 2015. This 96% reduction from an estimated...

WHO_SurveillanceVaccinePreventable_15_NonneonatalTetanus_R2_page1

Globally, approximately 13,500 tetanus cases were reported in 2016 through the WHO/UNICEF Joint Reporting Form, with 85% of cases occurring after the...

WHO_SurveillanceVaccinePreventable_21_Typhoid_R2_page1

Enteric fever (typhoid and paratyphoid fever) is caused by Salmonella enterica serovar Typhi (S. Typhi) and Salmonella enterica serovar Paratyphi (S....

WHO_SurveillanceVaccinePreventable_22_Varicella_R2_page1

Varicella-zoster virus (VZV) causes both varicella (chickenpox) by primary infection and herpes zoster (HZ or shingles) by endogenous reactivation...

WHO_SurveillanceVaccinePreventable_23_YellowFever_R1_page1

The purpose of this document is to provide World Health Organization (WHO)-recommended standards for conducting surveillance for vaccine preventable diseases...

WHO_SurveillanceVaccinePreventable_24_Annex1_R2_page1

As part of the national desk review, VPD surveillance should be assessed to understand the diseases under surveillance and to identify which need more...

WHO_SurveillanceVaccinePreventable_25_Annex2_R2_page1

This annex provides guidance on the use of serosurveys to estimate population immunity and monitor disease risk for tetanus.The aims of tetanus vaccination...

Documents forthcoming