Mental Health, Brain Health and Substance Use
Our work involves mental health promotion and the prevention of mental, neurological and substance use disorders. We support the expansion of access to affordable, quality care for everyone who needs it.
Antidepressants among adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective
[2012]
Recommendation(s)
When psychosocial interventions prove ineffective, fluoxetine (but not other Selective Serotonin Reuptake Inhibitors or Tricyclic Antidepressants) may be offered in adolescents with moderate-severe depressive episode/disorder. The intervention should only be offered under supervision of a specialist.
Strength of recommendation: CONDITIONAL
Quality of evidence: VERY LOW