Mental Health, Brain Health and Substance Use
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Role of Depot antipsychotic medicine in individuals requiring long-term antipsychotic treatment for psychotic disorders
2023 updated
Long-acting injection (LAI) antipsychotic medicines – namely fluphenazine, haloperidol, paliperidone, risperidone and zuclopenthixol – should be considered as an alternative to oral antipsychotic medicines for adults with psychotic disorders (including schizophrenia) requiring long-term treatment, carefully balancing effectiveness, side-effects and individual preference.
Strength of recommendation: CONDITIONAL
Certainty of evidence: MODERATE
[2012]
Recommendation(s)
In people with psychotic disorders (including schizophrenia) requiring long-term antipsychotic treatment, depot antipsychotics can be offered instead of oral medications as part of a treatment plan.
Strength of recommendation: CONDITIONAL
Quality of evidence: VERY LOW
Evidence Profile
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