e-Library of Evidence for Nutrition Actions (eLENA)


An online library of evidence-informed guidelines for nutrition interventions and single point of reference for the latest nutrition guidelines, recommendations and related information.

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Vitamin A fortification of staple foods

Intervention | Last updated: 9 August 2023


Vitamin A is important for visual health, immune function and fetal growth and development. Vitamin A deficiency is a public health problem in many parts of the world, particularly Africa and South-East Asia. It can cause visual impairment in the form of night blindness and, in children, may increase the risk of illness and death from childhood infections, including measles and those causing diarrhoea.

Fortification is the practice of deliberately increasing the content of an essential micronutrient, i.e. vitamins and minerals (including trace elements) in a food, so as to improve the nutritional quality of the food supply and provide a public health benefit with minimal risk to health.

Fortification of staple foods with vitamin A may be a cost-effective intervention for reducing vitamin A deficiency, especially in settings where improving dietary quality through food variety is not possible. Foods such as edible oils and fats, cereal grains, condiments, refined sugar and milk have been successfully fortified with vitamin A and studies have shown that consumption of vitamin A-fortified foods can improve vitamin A status.

Current research is aimed at further assessing the benefits and harms of fortifying staple foods on vitamin A status and health-related outcomes in the general population.

WHO Recommendations


Further research is needed before specific recommendations can be made.


Cost-effectiveness Learn More Alternate Text


Cost-effectiveness analyses


Cost effectiveness analysis of strategies for child health in developing countries

Edejer TT, Aikins M, Black R, Wolfson L, Hutubessy R, Evans DB. BMJ. 2005; 331(7526):1177.


Vitamin A fortification in Uganda: comparing the feasibility, coverage, costs, and cost-effectiveness of fortifying vegetable oil and sugar

Fiedler JL, Afidra R. Food Nutr Bull. 2010; 31(2):193-205.


A strategic approach to the unfinished fortification agenda: feasibility, costs, and cost-effectiveness analysis of fortification programs in 48 countries

Fiedler JL, Macdonald B. Food Nutr Bull. 2009; 30(4):283-316.


The costs and effectiveness of three vitamin A interventions in Guatemala

Phillips M, Sanghvi T, Suárez R, McKigney J, Fiedler J. Soc Sci Med. 1996; 42(12):1661-8.