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Rabies

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HUMAN AND ANIMAL RABIES

Rabies: A neglected zoonotic disease

Rabies is a vaccine-preventable disease, and it is still a significant public health problem in many countries of Asia and Africa, even though safe, effective vaccines for both human and veterinary use exist. Most of the   55 000 deaths from rabies reported annually around the world occur in Asia and Africa, and most of the victims are children: 30–50% of the reported cases of rabies—and therefore deaths—occur in children under 15 years of age. The main route of transmission is the bites of rabid dogs. Most of the children who die from rabies were not treated or did not receive adequate post-exposure treatment. Although the efficacy and safety of modern cell culture vaccines have been recognized, some Asian countries still produce and use nervous tissue vaccines, which are less effective, require repeated visits to the hospital and often have severe side-effects. Moreover, these patients do not receive the necessary rabies immunoglobulin, because of a perennial global shortage and because of its high price, so that it is unaffordable in countries where canine rabies is endemic.

Due to complete absence of any successful medical treatment for clinical rabies and the horrific nature of the disease, most rabies victims die at home rather than being admitted to a hospital in abysmal conditions. These circumstances add to the notorious lack of surveillance data. Underestimating the health implications of rabies leads many high ranking decision-makers in public health and animal health to perceive rabies as a rare disease of humans resulting from a bite of an uneconomically important animal (the dog). Therefore, rabies usually falls between two stools and is not dealt with appropriately either by the Ministry of Health or the Ministry of Agriculture.

:- Click here for the rabies fact sheet -:

MORE INFORMATION ON...

Animal rabies
Animal rabies
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Rabies epidemiology
Epidemiology
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Human rabies
Human rabies
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Vaccines and Immunization
Vaccines and immunization
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World Rabies Day 2008
28 September 2008
World Rabies Day

Read here about the first World Rabies Day in 2007.

Official WRD homepage


A WHO & BMGF JOINT PROJECT

Human rabies prevention through dog rabies elimination in selected developing countries. A Bill & Melinda Gates Foundation funded project coordinated by the WHO.
Full text


ACTIVE RABIES IMMUNIZATION WHERE RABIES VACCINES ARE IN SHORT SUPPLY

WHO recommendations for active rabies immunization after exposure where rabies vaccines are in short supply.
Full text


POST-EXPOSURE PROPHYLAXIS (PEP)

WHO's detailed guidelines on PEP treatment.
Full text [pdf 240kb]


RABNET

WHO has been collecting annual rabies data electronically through a standardized questionnaire of the rabies database system Rabnet.

Rabnet contact
rabnet@who.int


Essential rabies maps
Click here!