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Malaria transmission occurs in five WHO regions. Globally, an estimated 3.4 billion people in 92 countries are at risk of being infected with malaria and developing disease (map), and 1.1 billion are at high risk (>1 in 1000 chance of getting malaria in a year). According to the World Malaria Report 2018, there were 219 million cases of malaria globally in 2017 (uncertainty range 203–262 million) and 435 000 malaria deaths, representing a decrease in malaria cases and deaths rates of 18% and 28% since 2010, respectively. The burden was heaviest in the WHO African Region, where an estimated 93% of all malaria deaths occurred, and in children aged under 5 years, who accounted for 61% of all deaths.

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