Jonathan Torgovnik
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Cervical cancer

    Overview

    Cervical cancer develops in a woman's cervix (the entrance to the uterus from the vagina).  

    Almost all cervical cancer cases (99%) are linked to infection with high-risk human papillomaviruses (HPV), an extremely common virus transmitted through sexual contact.

    Although most infections with HPV resolve spontaneously and cause no symptoms, persistent infection can cause cervical cancer in women.

    Cervical cancer is the fourth most common cancer in women. In 2018, an estimated 570 000 women were diagnosed with cervical cancer worldwide and about 311 000 women died from the disease.

    Effective primary (HPV vaccination) and secondary prevention approaches (screening for, and treating precancerous lesions) will prevent most cervical cancer cases.

    When diagnosed, cervical cancer is one of the most successfully treatable forms of cancer, as long as it is detected early and managed effectively. Cancers diagnosed in late stages can also be controlled with appropriate treatment and palliative care.

    With a comprehensive approach to prevent, screen and treat, cervical cancer can be eliminated as a public health problem within a generation.

    Eliminating cervical cancer

    No woman should die from cervical cancer. We have the technical, medical and policy tools and approaches to eliminate it. The burden of cervical cancer falls on the women who lack access to health services, mainly in low-and middle income countries.

    In May 2018, the Director-General of  the World Health Organization announced a global call to action towards the elimination of cervical cancer, underscoring renewed political will to make elimination a reality, and called for all stakeholders to unite behind this common goal.

    In January 2019, the Executive Board requested the Director-General to develop a draft global strategy to accelerate cervical cancer elimination, with clear targets for the period 2020–2030. A Global Strategy towards the Elimination of Cervical Cancer as a Public Health Problem was developed in close consultation with Member States, and in collaboration with UN Agencies and other partners and organizations. It outlines key goals and agreed targets to be reached by 2030 and set the world on track to elimination.

    WHO Director-General speech

    WHO Director-General

    Cervical cancer: An NCD we can overcome

    Cervical Cancer Elimination Initiative Newsletter

    Publications

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    Human papillomavirus (‎HPV)‎ nucleic acid amplification tests (‎NAATs)‎ to screen for cervical pre-cancer lesions and prevent cervical cancer

    This policy brief focuses on the use of and the differences between HPV DNA-based and HPV mRNA-based molecular nucleic acid amplification tests...

    WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention, second edition: use of mRNA tests for human papillomavirus (‎HPV)‎

    This WHO and HRP guideline is designed to help countries make faster progress, more equitably, on the screening and treatment of cervical cancer....

    Generating Evidence for Artificial Intelligence Based Medical Devices: A Framework for Training Validation and Evaluation

    This first-of-its-kind publication from the WHO is a framework targeted at developers and researchers of AI-based software as a medical device, as well...

    Guidelines for the management of symptomatic sexually transmitted infections

    The WHO global health sector strategy on sexually transmitted infections (STIs), 2016–2021, endorsed by the World Health Assembly in 2016, aims to...

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