Target product profile for tuberculosis diagnosis and detection of drug resistance

Overview

The document consolidates two TPPs for TB diagnostics to be carried out at the peripheral level: a newly updated TPP for a rapid test for TB detection and a TPP released in 2021 on next-generation DST for M. tuberculosis. The updated and consolidated TPPs introduces, for the first time, definitions of classes of point-of-care (POC) tests and near-POC tests, and it relates these to the class of low-complexity diagnostic technologies currently recommended.