Mental Health, Brain Health and Substance Use
Our work involves mental health promotion and the prevention of mental, neurological and substance use disorders. We support the expansion of access to affordable, quality care for everyone who needs it.
Depression
Evidence-based recommendations for management of depression in non-specialized health settings
- Antidepressants (Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors) in treatment of adults with depression
- Duration of antidepressant treatment
- Brief, structured psychological treatment
- Behavioural activation
- Relaxation training
- Physical activity
- Antidepressant medication in comparison with psychological treatment for moderate-severe depressive disorder
- Comparative effectiveness of different formats of psychological treatments for depressive disorder
Related health topics
Publications

24 June 2019
mhGAP Intervention Guide - Version 2.0
This is the second version (2016) of the mhGAP Intervention Guide (mhGAP-IG) for mental, neurological and substance use (MNS) disorders in non-specialist...

1 January 2008
mhGAP Mental Health Gap Action Programme
Mental, neurological and substance use disorders are highly prevalent and burdensome globally. The gap between what is urgently needed and what is available...