United States of America
Partner in global health
A young girl is tested as part of lymphatic filariasis elimination efforts in Lao PDR. Partners and donors have supported activities including medication administration, monitoring visits, and a survey to assess the disease’s transmission.
This content was last updated on 23 December 2024.
A global force for health
Thanks to decades of strong partnership, the United States of America plays a crucial role in supporting WHO to protect and improve the health of Americans and people around the world.
The United States is a strong advocate for global health security. An example is the fight against polio, where the country is a key partner in the WHO-led eradication efforts, which protect Americans and communities worldwide from the resurgence of this preventable disease. The strong partnership between the United States and WHO for global health security supports other countries to improve their capacity in key health security areas. Similarly, the United States has been critical in delivering life-saving humanitarian assistance to communities devastated by conflict, natural disasters, and disease outbreaks.
In partnership with the United States, WHO is advancing innovation in health surveillance and biolab security to address emerging threats. Through improved monitoring and preparation of responses, WHO and the United States are working together to strengthen global resilience against health and security risks.
The United States has also been a strong proponent of WHO’s reform and transformation, promoting efficiency to ensure that WHO is better equipped to address global health challenges. This commitment includes leveraging domestic resources and expertise from the United States to strengthen capacity-building in other countries, helping to build resilient health systems capable of withstanding future health threats.
Globally, the United States maintains a strong presence in WHO collaborating centres, providing expertise across fields like cancer, mental health, nutrition, and chronic disease management, further reinforcing its commitment to global health leadership.

Spending the time to provide facts and listen to concerns increased vaccination acceptance in Lao PDR villages.
Response to outbreaks and emergencies
The United States of America and WHO are advancing global health security through their renewed five-year partnership, extending the Global Health Security Agenda (GHSA) to 2028, in support of accelerating implementation of the International Health Regulations (IHR). This initiative aims to help 100 countries achieve “Demonstrated Capacity” in key health security areas, with 58 Member States meeting this target by 2023. As of 2024, experts from the United States have supported nearly half of all WHO Joint External Evaluation (JEE) missions, reaffirming the country’s commitment to global preparedness.
In outbreak response, the Unites States has worked closely with WHO to stop emergencies such as the mpox outbreak in the Democratic Republic of Congo (DRC) and neighbouring countries. Since March 2024, the USA has contributed over US$ 22 million to mpox response efforts, supporting vaccine delivery and capacity building in six African countries. Support from the United States to WHO and Africa CDC for regulatory work towards delivery of vaccines has been critical to tackle the mpox outbreak.
Additionally, the United States partnered with Rwanda and WHO to address the Marburg virus disease (MVD) outbreak in 2024 through enhanced surveillance, contact tracing, and public health communication. These efforts reflect a strong dedication to tackling health crises collaboratively and effectively.
The United States and WHO share a long-standing partnership, delivering life-saving humanitarian assistance to communities devastated by conflict, natural disasters, and disease outbreaks. Leadership from the United States has been instrumental in protecting vulnerable populations—such as in Africa during the fight against deadly diseases like Ebola—and in ensuring health systems remain strong and responsive during crises. By supporting WHO’s emergency health efforts, the United States drives global health security, from preventing and preparing for future threats to delivering rapid response and recovery when it matters most.

Displaced from her home, a mother of three visits a mobile unit that provides primary health care in Iraq.
The United States shares its expertise through WHO collaborating centres
Collaborating centres are institutions that have been solid allies for years in helping WHO to implement its mandated work. WHO works with 68 collaborating centres hosted in the United States. The CDC has 17 collaborating centres, three of them in the Division of High-Consequence Pathogens and Pathology.
Since 1956, CDC’s Influenza Division has served as a collaborating centre for surveillance, epidemiology, and control of influenza in Atlanta, Georgia. It is the largest global centre supporting public health interventions to control and prevent pandemic and seasonal influenza.
USAID's Emerging Pandemic Threats 2 Program helps minimize the global impact of pandemic influenza threats, particularly from the H5N1 highly pathogenic avian flu. In addition, CDC’s Division of Global Health Protection serves as the collaborating centre for global public informatics, for biosafety and biosecurity, and for international health regulations.
CDC’s Viral Special Pathogens Branch supports WHO and Member States in the early diagnosis, rapid identification, and epidemiologic investigation of global high-risk pathogen outbreaks like Lassa Fever, Crimean-Congo Hemorrhagic Fever, Rift Valley Fever and Marburg virus.
Experts from the CDC provide technical guidance for national laboratories involved in outbreak response, as well as onsite laboratory diagnostic support with staff and equipment. These collaborations advance the world’s ability to prevent, detect, and respond to a wide range of health threats.
The National Institutes of Health, part of the U.S. Department of Health and Human Services, serves as a collaborating centre for global cancer control and health and the environment. The National Cancer Institute Center for Global Health and WHO have been able to promote the uptake of evidence-based cancer, advance cervical cancer elimination as a public health priority, and to strengthen data systems to monitor cancer prevention and control efforts.
Revered academic institutions in the United States also contribute to WHO through collaborating centres. These include Boston University, Columbia University, Johns Hopkins, National Cancer Institute, New York University, St. Jude Children's Research Hospital, and Yale University.