United States of America

United States of America

Partner in global health

WHO / Enric Catala
A young girl is tested as part of lymphatic filariasis elimination efforts in Lao PDR. Partners and donors have supported activities including medication administration, monitoring visits, and a survey to assess the disease’s transmission.
© Credits

This content was last updated on 23 December 2024.

A global force for health

Thanks to decades of strong partnership, the United States of America plays a crucial role in supporting WHO to protect and improve the health of Americans and people around the world.

The United States is a strong advocate for global health security. An example is the fight against polio, where the country is a key partner in the WHO-led eradication efforts, which protect Americans and communities worldwide from the resurgence of this preventable disease. The strong partnership between the United States and WHO for global health security supports other countries to improve their capacity in key health security areas. Similarly, the United States has been critical in delivering life-saving humanitarian assistance to communities devastated by conflict, natural disasters, and disease outbreaks.

In partnership with the United States, WHO is advancing innovation in health surveillance and biolab security to address emerging threats. Through improved monitoring and preparation of responses, WHO and the United States are working together to strengthen global resilience against health and security risks.

The United States has also been a strong proponent of WHO’s reform and transformation, promoting efficiency to ensure that WHO is better equipped to address global health challenges. This commitment includes leveraging domestic resources and expertise from the United States to strengthen capacity-building in other countries, helping to build resilient health systems capable of withstanding future health threats. 

Globally, the United States maintains a strong presence in WHO collaborating centres, providing expertise across fields like cancer, mental health, nutrition, and chronic disease management, further reinforcing its commitment to global health leadership.

 


©WHO
Spending the time to provide facts and listen to concerns increased vaccination acceptance in Lao PDR villages.
© Credits

   

For decades, a leading donor

Graph showing the top 10 contributors to WHO for the biennium 2022-23: United States of America, Germany, Bill & Belinda Gates Foundation, Gavi, European Comission, UK, Canada, Rotary International, Japan, and France.

Note: The amounts represent the revenue received by WHO for the period stated and they might differ from the figures in the WHO Budget Portal, as they represent funds available net of programme support costs.

The United States of America is the top donor and partner to WHO, contributing through assessed contributions and voluntary funding. The United States contributed US$ 1.284 billion during the 2022–2023 biennium, enabling work by WHO, the United States and other countries and partners to identify and respond to emergencies, stop disease threats from spreading across borders and advance other key global health priorities. Contributions help keep the United States and the world safe from threats while supporting better health and well-being for populations around the world, with a focus on the most vulnerable.

WHO is grateful to all the institutions of the Government of the United States of America that contribute with funding and expertise, including the U.S. Department of State, U.S. Department of Health and Human Services, the Centers for Disease Control (CDC), the Environmental Protection Agency (EPA), the United States President’s Emergency Plan for AIDS Relief (PEPFAR) and U.S. Agency for International Development (USAID).

   

Response to outbreaks and emergencies

The United States of America and WHO are advancing global health security through their renewed five-year partnership, extending the Global Health Security Agenda (GHSA) to 2028, in support of accelerating implementation of the International Health Regulations (IHR). This initiative aims to help 100 countries achieve “Demonstrated Capacity” in key health security areas, with 58 Member States meeting this target by 2023. As of 2024, experts from the United States have supported nearly half of all WHO Joint External Evaluation (JEE) missions, reaffirming the country’s commitment to global preparedness.

In outbreak response, the Unites States has worked closely with WHO to stop emergencies such as the mpox outbreak in the Democratic Republic of Congo (DRC) and neighbouring countries. Since March 2024, the USA has contributed over US$ 22 million to mpox response efforts, supporting vaccine delivery and capacity building in six African countries. Support from the United States to WHO and Africa CDC for regulatory work towards delivery of vaccines has been critical to tackle the mpox outbreak.

Additionally, the United States partnered with Rwanda and WHO to address the Marburg virus disease (MVD) outbreak in 2024 through enhanced surveillance, contact tracing, and public health communication. These efforts reflect a strong dedication to tackling health crises collaboratively and effectively.

The United States and WHO share a long-standing partnership, delivering life-saving humanitarian assistance to communities devastated by conflict, natural disasters, and disease outbreaks. Leadership from the United States has been instrumental in protecting vulnerable populations—such as in Africa during the fight against deadly diseases like Ebola—and in ensuring health systems remain strong and responsive during crises. By supporting WHO’s emergency health efforts, the United States drives global health security, from preventing and preparing for future threats to delivering rapid response and recovery when it matters most.


A woman enters a mobile health clinic whilst as a man is waiting next in line.
© WHO
Displaced from her home, a mother of three visits a mobile unit that provides primary health care in Iraq.
© Credits

   

Primary health care and global health workforce

The United States and WHO are driving global health improvements through the Global Action Plan to Accelerate Primary Healthcare, focusing on strengthening health systems and advancing universal health coverage. Efforts include boosting investments in resilient health-care systems and expanding the global health workforce to ensure preparedness and health gains worldwide.

In Africa, the United States supported WHO’s launch of the Health Workforce Investment Charter to address critical health worker needs. In the Americas, the United States and PAHO trained over 263 000 health workers through the Americas Health Corps, targeting 500 000 trained professionals by 2027. Additionally, USAID and WHO collaborated to enhance labor standards for health workers under the WHO Global Health and Care Worker Compact, ensuring better protection and equitable employment for community-health workers. These initiatives highlight the country’s commitment to empowering health workforces and strengthening global health systems.

   

Regulatory systems strengthening

The U.S. Department of Health and Human Services, through the FDA, supports the African Vaccine Regulatory Forum (AVAREF) to conduct clinical trials for vaccines and other medical products that are a public health priority for the continent, bolstering Africa’s capacity for vaccine and medical product regulation. This initiative ensures timely evaluation of vaccines during public health emergencies, such as the mpox outbreak.

Through collaboration with WHO’s regulatory strengthening program and the Global Benchmarking Tool, FDA assistance has helped multiple African countries enhance their regulatory systems, with six additional countries achieving Maturity Level 3 since 2022. The support from the United States towards these efforts are vital for advancing public health priorities across the continent and enhancing global health security.

   

WHO Uganda
Among the key measures to curb the spread of mpox, Ugandan health authorities, with support from WHO and partners, are working closely with communities to raise awareness about the disease.
© Credits

Digital health for stronger health data

The United States and WHO are partnering to strengthen digital health systems in in low- and middle-income countries, enhancing equitable access to care. In Africa, integrating immunization data into DHIS2 platforms in 12 countries has enabled real-time health tracking, helping identify underserved populations and “zero-dose” children. GIS-based mapping through the WHO Geolocated Health Facilities Data initiative has further supported countries like Nigeria, Ethiopia, and Mozambique in addressing health disparities and improving interventions, also reaching thousands of unvaccinated children in Chad and Cameroon.

The USA–WHO collaboration also plays a pivotal role in combating global HIV, advancing the 95-95-95 targets to end HIV as a public health threat by 2030. By fostering the use of longitudinal, person-centered data and implementing WHO recommendations on testing, treatment, and PrEP for prioritized populations, this partnership ensures accountability and improved service delivery. Coordination with global partners like UNAIDS and the Global Fund extends the impact of these critical efforts.

A more efficient WHO

The United States is supporting WHO’s ongoing reforms to enhance efficiency, accountability, and transparency, ensuring the organization remains fit to address global health challenges. Key reforms include budget and management improvements to optimize resource use and drive impactful results.

Significant strides have also been made in preventing and responding to sexual exploitation, abuse, and harassment (PRSEAH). WHO has implemented over 90% of the 150 actions outlined in its Management Response Plan, including revising policies to close accountability gaps and establish a Prevention of and Response to Sexual Misconduct (PRSM) department. With support from the United States, WHO adopted a victim-centered approach, introduced mandatory staff training, and uses ClearCheck background screening for new hires.

Operationally, PRSEAH measures are now integrated into WHO’s health emergency responses, including mpox and Marburg plans. Dedicated teams and tools have strengthened emergency preparedness and response capacities across WHO and its partners. Sustaining these reforms is essential to maintaining WHO’s effectiveness and safeguarding vulnerable populations.

   

The United States shares its expertise through WHO collaborating centres

Collaborating centres are institutions that have been solid allies for years in helping WHO to implement its mandated work. WHO works with 68 collaborating centres hosted in the United States. The CDC has 17 collaborating centres, three of them in the Division of High-Consequence Pathogens and Pathology. 

Since 1956, CDC’s Influenza Division has served as a collaborating centre for surveillance, epidemiology, and control of influenza in Atlanta, Georgia. It is the largest global centre supporting public health interventions to control and prevent pandemic and seasonal influenza.

USAID's Emerging Pandemic Threats 2 Program helps minimize the global impact of pandemic influenza threats, particularly from the H5N1 highly pathogenic avian flu. In addition, CDC’s Division of Global Health Protection serves as the collaborating centre for global public informatics, for biosafety and biosecurity, and for international health regulations.

CDC’s Viral Special Pathogens Branch supports WHO and Member States in the early diagnosis, rapid identification, and epidemiologic investigation of global high-risk pathogen outbreaks like Lassa Fever, Crimean-Congo Hemorrhagic Fever, Rift Valley Fever and Marburg virus.

Experts from the CDC provide technical guidance for national laboratories involved in outbreak response, as well as onsite laboratory diagnostic support with staff and equipment. These collaborations advance the world’s ability to prevent, detect, and respond to a wide range of health threats.

The National Institutes of Health, part of the U.S. Department of Health and Human Services, serves as a collaborating centre for global cancer control and health and the environment. The National Cancer Institute Center for Global Health and WHO have been able to promote the uptake of evidence-based cancer, advance cervical cancer elimination as a public health priority, and to strengthen data systems to monitor cancer prevention and control efforts.

Revered academic institutions in the United States also contribute to WHO through collaborating centres. These include Boston University, Columbia University, Johns Hopkins, National Cancer Institute, New York University, St. Jude Children's Research Hospital, and Yale University.