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Cancer

    Overview

    Cancer is the uncontrolled growth and spread of cells that arises from a change in one single cell. The change may be started by external agents and/or inherited genetic factors and can affect almost any part of the body. The transformation from a normal cell into a tumour cell is a multistage process where growths often invade surrounding tissue and can metastasize to distant sites. These changes result from the interaction between a person’s genetic factors and any of 3 categories of external agents:

    • physical carcinogens, such as ultraviolet and ionizing radiation or asbestos;
    • chemical carcinogens, such as vinyl chloride, or betnapthylamine (both rated by the International Agency for Research into Cancer as carcinogenic), components of tobacco smoke, aflatoxin (a food contaminant) and arsenic (a drinking-water contaminant); and
    • biological carcinogens, such as infections from certain viruses, bacteria or parasites.

    Most chemicals to which people are exposed in everyday life have not been tested for their long-term impact on human health.

    Many cancers can be prevented by avoiding exposure to common risk factors, such as tobacco smoke. In addition, a significant proportion of cancers can be cured, by surgery, radiotherapy or chemotherapy, especially if they are detected early.

    Impact

    Cancer is the most important cause of death and morbidity in Europe after cardiovascular diseases. With more than 3.7 million new cases and 1.9 million deaths each year, cancer represents the second most important cause of death and morbidity in Europe.

    WHO response

    WHO/Europe assists countries to develop national programmes for cancer control. The International Agency for Research on Cancer (IARC) is the WHO body that specializes in this field. It coordinates and conducts research on causes and develops scientific strategies for cancer prevention and control.

    20%

    The percentage of deaths caused by cancer in the European Region

    Our work

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    Preventing and treating cancer

    Preventing and treating cancer

    Overview

    The WHO Regional Office for Europe contributes to cancer prevention and treatment in the following ways:

    • identifying the scale of the problem and the capacity of countries to respond, and assisting individual countries with their own situation analyses;
    • supporting countries in the development, implementation and evaluation of national cancer control programmes;
    • working on early detection through the development of early diagnosis and screening programmes for breast and cervical cancer;
    • strengthening health and social care systems for the management of chronic disease, for example through access to essential medicines, and reforms of primary care systems to become more responsive;
    • building capacity for palliative care through national palliative care programmes, strengthening of primary care and health service delivery, training of health workers on palliative care principles and pain management and increasing access to oral morphine;
    • assisting countries in surveillance of diseases and their risk factors including risk factor surveys, cancer registries and cancer screening registries;
    • facilitating the exchange of good practice between countries through international meetings, subregional workshops, producing and disseminating information; and
    • building alliances with other agencies and nongovernmental organizations and collaborating to raise awareness and the need for an adequate response.

    Policy interventions

    Part of this work involves supporting countries in the implementation of international commitments to take action. For example, as Parties to the WHO Framework Convention on Tobacco Control, many countries in the Region have introduced population-based interventions policies, including raising tobacco and alcohol taxes and prices, warning people about the dangers of tobacco and harmful use of alcohol, and enforcing bans on tobacco and alcohol advertising.

    4 pillars

    WHO’s approach to cancer has 4 pillars: prevention, early detection, diagnosis and treatment and palliative care. A comprehensive cancer strategy addresses all these areas acknowledging certain facts.

    • At least one third of cancer cases are preventable through reducing tobacco and alcohol use, moderating diet and immunizing against human papillomavirus and viral hepatitis B.
    • Early detection and prompt treatment can reduce cancer mortality by a further one third.
    • Effective techniques are sufficiently well established to permit comprehensive palliative care for the remaining more advanced cases.

    WHO has consolidated tools for countries in a framework known as the national cancer control programme, which focuses government attention and services on all facets of the fight against cancer. This public health programme is designed to reduce cancer incidence and mortality, and to improve cancer patients’ quality of life, through the systematic and equitable implementation of evidence-based strategies for prevention, early detection, diagnosis, treatment and palliation, making the best use of available resources.

    Cancer control should be part of a more comprehensive strategy for the prevention and control of noncommunicable diseases. The strategy should simultaneously promote population-level health promotion and disease prevention, and actively target groups and individuals at high risk, while maximizing population coverage with effective treatment and care. Tackling the wider determinants of health and reducing inequalities within and between countries has the potential to contribute to major improvements. In collaboration with partners and Member States, WHO has developed comprehensive strategies and guidelines, both at global and regional levels, to tackle the risk factors that lead to cancer and other noncommunicable diseases.

    Multimedia

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    Infographics

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    Publications

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    Avoidable mortality, risk factors and policies for tackling noncommunicable diseases – leveraging data for impact: monitoring commitments in the WHO European Region ahead of the Fourth United Nations High-Level Meeting
    The report notes that, in order to tackle NCDs and address the commercial, social, environmental and digital determinants of health, there is a need for...
    Review of the Republic of Moldova's approach to noncommunicable diseases during the emergency response to the 2022 influx of Ukrainian refugees

    The scale of the refugee influx in 2022 following the outbreak of war in Ukraine was unprecedented; it resulted in substantial health needs for the affected...

    Alcohol health warning labels: a public health perspective for Europe

    In the European Union the per capita alcohol consumption among adults (‎15+ years)‎ in 2019 was twice the world average, with one in 19 adults...

    Documents

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    The clock is ticking. With just five years left to achieve 2030 Sustainable Development Goal (SDG) 3.4 of reducing premature deaths from noncommunicable...

    In too many countries, the majority of women are diagnosed too late, multidisciplinary treatment and follow-up care are suboptimal, and supportive and...

    Related WHO collaborating centres

    WHO collaborating centres are institutions that form an international collaborative network carrying out activities to support WHO’s programmes at all levels. They provide an opportunity for WHO to utilize their inherent expertise for the benefit of all Member States.

    View the list of related collaborating centres