Preparing and preventing epidemics and pandemics

The number of high-threat infectious hazards continues to rise; some of these are re-emerging and others are new. While outbreaks of vaccine-preventable infectious diseases, such as meningococcal disease, yellow fever and cholera, can have disastrous effects in areas with limited health infrastructure and resources, and where timely detection and response is difficult.

WHO develops global strategies for the prevention and control of epidemic-prone diseases, such as yellow fever, cholera and influenza. With partners from a wide range of technical, scientific and social fields, WHO brings together all globally available resources to counter these high-threat infectious hazards and scale these strategies to regional and country levels. 

Flagship global strategies include: 

  • the Eliminate Yellow Fever Epidemics strategy 2017-2026;
  • Ending Cholera: a Global Roadmap to 2030;
  • the Pandemic Influenza Preparedness (PIP) Framework; and 
  • the Global Strategy for Influenza 2018-2030.

WHO is also the secretariat for the governance of global emergency stockpiles, including the International Coordinating Group on Vaccine Provision, which manages and coordinates the provision of emergency vaccine supplies and antibiotics to countries during major outbreaks.

Our work

Measuring the effectiveness and impact of public health and social measures

Measuring the effectiveness and impact of public health and social measures

Overview

Public health and social measures (PHSM) refer to non-pharmaceutical interventions implemented by individuals, communities and governments to protect the health and well-being of communities affected by health emergencies. PHSM reduce the risk and scale of transmission of infectious diseases by reducing transmission-relevant exposures and/or making them safer. Examples of PHSM include hand washing, mask-wearing, physical distancing, school and business measures, modifications of mass gatherings and international travel and trade measures.

PHSM are often the first and sometimes the only intervention available at the onset of an outbreak when effective vaccines and therapeutics are not (yet) available or equitably distributed. PHSM play a critical role throughout the different stages of health emergencies and act in concert with medical countermeasures.

Recent health emergencies revealed, however, that individuals and communities experienced unintended negative consequences of PHSM (intervention burden) above and beyond the burden of health and health inequities by COVID-19 itself. This intervention burden includes unemployment, interrupted education, domestic violence and slowing economic productivity. People living in vulnerable conditions disproportionately experienced this intervention burden and hence highlighted the critical importance of social protection policies and other mitigation measures. 

The WHO PHSM initiative on measuring the effectiveness and impact of public health and social measures (PHSM) during health emergencies aims to: 

  • accelerate multidisciplinary, multisectoral research on the effectiveness of PHSM, unintended negative consequences and implementation strategies; 
  • strengthen evidence-informed and context-specific PHSM decision-making; and 
  • expand the effective and equitable implementation of PHSM alongside medical countermeasures in health emergency preparedness and response for emerging and re-emerging infectious hazards.

 

Publications

All →
Guidance on regulations for the transport of infectious substances 2025-2026: applicable as from 1 October 2025

Ensuring the safe transport of infectious substances is essential to protect public health and prevent accidental exposure during increasingly complex...

Report of the WHO biosafety and biosecurity inspection team of the Variola Virus maximum containment laboratories to the Centers for Disease Control and Prevention (CDC): Atlanta, Georgia, United States of America, 27 April-1 May 2026

Ensuring the safe and secure handling of variola virus remains a critical global public health priority, given its historical impact and the risks associated...

WHO guideline on public health and social measures for mitigating the risk and impact of epidemic and pandemic influenza

Influenza virus infections cause acute respiratory illness that is usually self-limiting but can be severe in some cases. Each year, seasonal influenza...

Indicators for human exposures to zoonotic pathogens

This report presents a WHO–PREZODE collaboration to develop and validate standardized indicators that assess the risk of zoonotic disease emergence...